【产品概况】
产品名称:Human TRP1 / TYRP1 Antibody (Flanvotumab, Research Use)
产品编号:NBR-0622
针对靶点:TRP1 / TYRP1
抗体药商品名:Flanvotumab
抗体药描述:Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab has potent anti-tumor activity and good tolerance.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TRP1
Synonyms: HTRP-1; Short Transient Receptor Potential Channel 1; TRPC1
Target Description: TRPC1 (Transient Receptor Potential Cation Channel Subfamily C Member 1) is a Protein Coding gene. Diseases associated with TRPC1 include Pyloric Stenosis and Immunodeficiency 10. Among its related pathways are Cardiac conduction and Nervous system development. Gene Ontology (GO) annotations related to this gene include monoatomic ion channel activity and calcium channel activity. An important paralog of this gene is TRPC4.
Ensembl: ENSG00000144935
Uniprot: P48995