产品名称：Human CTLA-4 / CD152 Antibody (Zalifrelimab, Research Use)
产品编号：NBR-0625
针对靶点：CTLA-4 / CD152
抗体药商品名：Zalifrelimab
抗体药描述：Zalifrelimab is an antibody, a protein designed to interact with a specific target, that binds to and blocks CTLA4. This prevents CTL4 from binding to its targets, which reduces the CTLA-4-mediated inhibition of T-cells. It is hoped that through this mechanism, zalifrelimab will cause an increase in the number of activated T-cells in the tumor environment, allowing the immune system to effectively target and kill the cancer's cells. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: CD152
Synonyms: CD152; GSE; CD
Target Description: CTLA4 (Cytotoxic T-Lymphocyte Associated Protein 4) is a Protein Coding gene. Diseases associated with CTLA4 include Immune Dysregulation With Autoimmunity, Immunodeficiency, And Lymphoproliferation and Celiac Disease 3. Among its related pathways are Gene expression (Transcription) and CD28 co-stimulation. An important paralog of this gene is CD28.
Ensembl: ENSG00000163599
Uniprot: P16410