【产品概况】
产品名称:Human CTLA-8 / IL-17a Antibody (Perakizumab, Research Use)
产品编号:NBR-0629
针对靶点:CTLA-8 / IL-17a
抗体药商品名:Perakizumab
抗体药描述:Perakizumab is a recombinant humanized (from mouse) IgGκ monoclonal antibody (mAb) binds to and neutralises the proinflammatory cytokine interleukin-17A (IL-17A). It was discovered and developed by Roche/Genentech) with the developmental name RG4934 (RO5310074), for the treatment of autoimmune diseases such as psoriasis, psoriatic arthritis, ankylosing spondylitis, multiple sclerosis and inflammatory arthritis.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CTLA-8
Synonyms: IL-17A; IL-17; CTLA8
Target Description: IL17A (Interleukin 17A) is a Protein Coding gene. Diseases associated with IL17A include Allergic Contact Dermatitis and Bronchiolitis Obliterans. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17F.
Ensembl: ENSG00000112115
Uniprot: Q16552