【产品概况】
产品名称:Human TGFb1 Antibody (Fresolimumab, Research Use)
产品编号:NBR-0642
针对靶点:TGFb1
抗体药商品名:Fresolimumab
抗体药描述:Fresolimumab (GC1008), a human IgG4κ monoclonal antibody that neutralizes TGFβ1, 2, and 3, demonstrated acceptable safety and antitumor activity in a phase 1 clinical trial for patients with malignant melanoma or renal carcinoma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TGFB1
Synonyms: CED; DPD1; TGFB; TGFbeta
Target Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
Ensembl: ENSG00000105329
Uniprot: TGFB1