Human PCSK9 Antibody (Frovocimab, Research Use)

产品名称	Human PCSK9 Antibody (Frovocimab, Research Use)
目录号	NBR-0643
别名	FH3; HCHOLA3; NARC-1
外观	Transparent Liquid
分子量	150kDa
CAS	N/A
溶解度	Water, PBS, TBS Buffer,etc.
存储条件	Temp. -80℃
保存时间	see COA
备注1	CHO Expressed
备注2	Ab. Isotype - IgG

目录号	规格	价格	库存状态
NBR-0643-100UG	100ug	￥550	请咨询
NBR-0643-1MG	1mg	￥3500	请咨询
NBR-0643-5MG	5mg	￥7500	请咨询

【产品概况】

产品名称：Human PCSK9 Antibody (Frovocimab, Research Use)
产品编号：NBR-0643
针对靶点：PCSK9
抗体药商品名：Frovocimab
抗体药描述：Frovocimab (LY 3015014) is a humanized IgG4 monoclonal antibody (mAb) that neutralizes PCSK9. Frovocimab inhibits PCSK9 binding to LDL receptor (LDLR) while permitting the normal proteolytic cleavage of the bound intact PCSK9.

【产品参数】

产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

【基因信息】

Gene Name: PCSK9
Synonyms: FH3; HCHOLA3; NARC-1
Target Description: Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.
Ensembl: ENSG00000169174
Uniprot: Q8NBP7