【产品概况】
产品名称:Human EGFL7 Antibody (Parsatuzumab, Research Use)
产品编号:NBR-0647
针对靶点:EGFL7
抗体药商品名:Parsatuzumab
抗体药描述:Parsatuzumab (also known as MEGF0444A) is a humanized IgG1 monoclonal antibody that selectively blocks the interaction between EGFL7 and endothelial cells. In preclinical models, the addition of anti-EGFL7 enhanced the antiangiogenesis, tumor growth control, and survival associated with anti-VEGF monotherapy.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: EGFL7
Synonyms: ZNEU1
Target Description: Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.
Ensembl: ENSG00000172889
Uniprot: Q9UHF1