【产品概况】
产品名称:Human ERBB1 / EGFR / HER1 Antibody (Zalutumumab, Research Use)
产品编号:NBR-0667
针对靶点:ERBB1 / EGFR / HER1
抗体药商品名:Zalutumumab
抗体药描述:Zalutumumab is a recent high-affinity completely human IgG1k antibody targeting EGFR .Zalutumumab has demonstrated acceptable toxicity in head and neck cancer patients, with rash being the most common adverse event.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533