【产品概况】
产品名称:Human ERBB2 / HER2 / CD340 Antibody (Hersintuzumab, Research Use)
产品编号:NBR-0671
针对靶点:ERBB2 / HER2 / CD340
抗体药商品名:Hersintuzumab
抗体药描述:Hersintuzumab is a humanized mAb that targets HER2 extracellular domains I-II. In HER2-positive tumor xenograft models, the combination of hersintuzumab and trastuzumab inhibited tumor cell growth and showed the strongest antitumor activity in ovarian cancer and GC xenograft models .
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ERBB2
Synonyms: HER2; C-ERB-2; CD340
Target Description: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
Ensembl: ENSG00000141736
Uniprot: P04626