【产品概况】
产品名称:Human ERBB2 / HER2 / CD340 Antibody (Margetuximab, Research Use)
产品编号:NBR-0672
针对靶点:ERBB2 / HER2 / CD340
抗体药商品名:Margetuximab
抗体药描述:The second-generation anti-human epidermal growth factor receptor2 protein (HER2) monoclonal antibody margetuximab is being developed for the treatment of HER2-positive breast cancer, gastric cancer and gastro-oesophageal junction cancer.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ERBB2
Synonyms: HER2; C-ERB-2; CD340
Target Description: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone.
Ensembl: ENSG00000141736
Uniprot: P04626