产品名称：Human ERBB3 / HER3 Antibody (Barecetamab, Research Use)
产品编号：NBR-0674
针对靶点：ERBB3 / HER3
抗体药商品名：Barecetamab
抗体药描述：Barecetamab (ISU 104) is a highly potent, fully human anti-ErbB3 monoclonal antibody, binds potently and specifically to the NRG1 binding region of domain 3 of ErbB3, exhibits potent antitumorigenic activity. Barecetamab (ISU 104) inhibited ligand binding, ligand-dependent heterodimerization and phosphorylation, and induced the internalization of ErbB3. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: ERBB3
Synonyms: HER3; LCCS2
Target Description: This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation.
Ensembl: ENSG00000065361
Uniprot: P21860