【产品概况】
产品名称:Human FcRL5 / IRTA2 Antibody (DFRF4539A, Research Use)
产品编号:NBR-0680
针对靶点:FcRL5 / IRTA2
抗体药商品名:DFRF4539A
抗体药描述:DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. This phase I study assessed safety, tolerability, maximum tolerated dose (MTD), anti-tumor activity, and pharmacokinetics of DFRF4539A in patients with relapsed/refractory multiple myeloma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FcRL5
Synonyms: BXMAS1; CD307e; FCRH5; IRTA2
Target Description: May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
Ensembl: ENSG00000143297
Uniprot: Q96RD9