【产品概况】
产品名称:Human Sortilin / SORT1 Antibody (Latozinemab, Research Use)
产品编号:NBR-0696
针对靶点:Sortilin / SORT1
抗体药商品名:Latozinemab
抗体药描述:Latozinemab (formerly AL 001) is a microglia activating recombinant human anti-human sortilin (SORT1) monoclonal antibody, being developed by Alector.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: SORT1
Synonyms: Sortilin 1; Gp95; NT3
Target Description: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR).
Ensembl: ENSG00000134243
Uniprot: Q99523