【产品概况】
产品名称:Human CD47 Antibody (Lemzoparlimab, Research Use)
产品编号:NBR-0697
针对靶点:CD47
抗体药商品名:Lemzoparlimab
抗体药描述:Lemzoparlimab (also known as TJ011133 or TJC4) is a differentiated CD47 IgG4 antibody targeting a distinct CD47 epitope to enable a unique red blood cell sparing property, while retaining strong anti-tumor activity as demonstrated previously in patients with solid tumors.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD47
Synonyms: IAP; MER6; OA3
Target Description: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity).
Ensembl: ENSG00000196776
Uniprot: Q08722