【产品概况】
产品名称:Human IGF1R / CD221 Antibody (LonigutamAb, Research Use)
产品编号:NBR-0702
针对靶点:IGF1R / CD221
抗体药商品名:LonigutamAb
抗体药描述:Lonigutamab (VB-421) is a subcutaneously delivered anti-IGF-1R that is currently being evaluated in a phase 1 study for thyroid eye disease. It is estimated to be a market opportunity worth over $4 billion.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IGF1R
Synonyms: CD221; IGFIR; IGFR; JTK13; MGC18216
Target Description: Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.
Ensembl: ENSG00000140443
Uniprot: P08069