【产品概况】
产品名称:Human ERBB1 / EGFR / HER1 Antibody (Modotuximab, Research Use)
产品编号:NBR-0713
针对靶点:ERBB1 / EGFR / HER1
抗体药商品名:Modotuximab
抗体药描述:Modotuximab, also known as zatuximab, is a recombinant human-mouse chimeric monoclonal antibody (mAb) designed by Symphogen for the treatment of metastatic colorectal cancer (mCRC) and glioblastoma (GBM).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533