【产品概况】
产品名称:Human FcRn (FCGRT & B2M) Antibody (Nipocalimab, Research Use)
产品编号:NBR-0730
针对靶点:FcRn (FCGRT & B2M)
抗体药商品名:Nipocalimab
抗体药描述:Nipocalimab (M281) is a fully human, recombinant, aglycosylated IgG1 monoclonal antibody. Nipocalimab is a human deglycosylated IgG1 anti-FcRn monoclonal antibody that binds with picomolar affinity to Fc receptor (FcRn) at both endosomal pH 6.0 and extracellular pH 7.6.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: FcRn
Synonyms: Fc Receptor
Target Description: Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk.
Ensembl: ENSG00000104870
Uniprot: P55899