【产品概况】
产品名称:Human PTPRC / CD45 Antibody (Novartis patent anti-CD45, Research Use)
产品编号:NBR-0740
针对靶点:PTPRC / CD45
抗体药商品名:Novartis patent anti-CD45
抗体药描述:The drug is a recombinant fully human anti-CD45 monoclonal antibody, being developed by Novartis.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PTPRC
Synonyms: T200; GP180; CD45; LCA; IMD105; B220
Target Description: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN.
Ensembl: ENSG00000081237
Uniprot: P08575