【产品概况】
产品名称:Human IL-1a Antibody (Bermekimab, Research Use)
产品编号:NBR-0743
针对靶点:IL-1a
抗体药商品名:Bermekimab
抗体药描述:Bermekimab (MABp1) is a first-in-class true human monoclonal antibody cloned directly from human B lymphocytes that specifically targets and neutralizes IL-1α. The drug has been tested so far in three randomized clinical trials (RCTs) in disease areas; metastatic colon carcinoma and hidradenitis suppurativa (HS). HS is a chronic devastating skin disorder that affects skin areas rich in apocrine glands.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-1a
Synonyms: IL1F1; Hematopoietin-1;
Target Description: Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems.
Ensembl: ENSG00000115008
Uniprot: P01583