【产品概况】
产品名称:Human IL-21 Antibody (Avizakimab, Research Use)
产品编号:NBR-0748
针对靶点:IL-21
抗体药商品名:Avizakimab
抗体药描述:Avizakimab (BOS161721) is a humanized IgG1 monoclonal antibody that targets interleukin-21. Avizakimab (BOS161721) prevents IL-21 binding to the IL-21 receptor (IL-21R) and inhibits bioactivity.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-21
Synonyms: Za11; CVID11
Target Description: Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). Implicated in the generation and maintenance of T follicular helper (Tfh) cells and the formation of germinal-centers.
Ensembl: ENSG00000138684
Uniprot: Q9HBE4