【产品概况】
产品名称:Human IL-23 Antibody (LY2525623, Research Use)
产品编号:NBR-0750
针对靶点:IL-23
抗体药商品名:LY2525623
抗体药描述:LY2525623 is an anti-IL-23p19 antibody developed by Eli. Lilly that has recently been tested in a randomized, dou-ble-blind, dose-finding phase II t rial.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-23
Synonyms: SGRF; IL-23a; P19;
Target Description: Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity. Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.
Ensembl: ENSG00000110944
Uniprot: Q9NPF7