【产品概况】
产品名称:Human TIGIT Antibody (Ociperlimab, Research Use)
产品编号:NBR-0755
针对靶点:TIGIT
抗体药商品名:Ociperlimab
抗体药描述:Ociperlimab (BGB-A1217) is a humanized IgG1 monoclonal antibody developed by Beigene and developed worldwide. As an immune checkpoint candidate, ociperlimab is one of the most advanced anti-Tigit (T cell immunoglobulin and ITIM domain protein) antibodies currently in development with complete Fc function.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TIGIT
Synonyms: DKFZp667A205; FLJ39873; VSIG9; VSTM3
Target Description: Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
Ensembl: ENSG00000181847
Uniprot: Q495A1