【产品概况】
产品名称:Human IL-4Ra / CD124 Antibody (MEDI2045, Research Use)
产品编号:NBR-0759
针对靶点:IL-4Ra / CD124
抗体药商品名:MEDI2045
抗体药描述:MEDI2045 is an IL-4Ra-neutralising antibody for the treatment of tevere uncontrolled asthma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-4Ra
Synonyms: CD124
Target Description: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation.
Ensembl: ENSG00000077238
Uniprot: P24394