产品名称：Human IL-6 / IFNb2 Antibody (Sirukumab, Research Use)
产品编号：NBR-0769
针对靶点：IL-6 / IFNb2
抗体药商品名：Sirukumab
抗体药描述：Sirukumab is a human monoclonal antibody that selectively binds to the IL-6 cytokine. The phase III, multicentre, randomised, double-blind, placebo-controlled, parallel-group SIRROUND-D study (ClinicalTrials.gov identifier NCT01604343) evaluated the efficacy and safety of sirukumab in patients with active RA refractory to disease-modifying antirheumatic drugs. 产品外观：Transparent Liquid
分子量：~150kDa
CAS：N/A
溶解度：Water; PBS, TBS Buffer等
表达系统：CHO Expressed
抗体亚型：Ab. Isotype - IgG

  Gene Name: IL-6
Synonyms: IL-6; IFNB2; BSF2; HGF; HSF; BSF-2; CDF
Target Description: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable).
Ensembl: ENSG00000136244
Uniprot:  P05231