【产品概况】
产品名称:Human IL-6 / IFNb2 Antibody (Olokizumab, Research Use)
产品编号:NBR-0774
针对靶点:IL-6 / IFNb2
抗体药商品名:Olokizumab
抗体药描述:Olokizumab is a humanized monoclonal antibody that represses the IL-6 pathway by attaching to the 3rd attachment site of IL-6 and blocking its interaction with gp130. It has been previously used as an anti-inflammatory agent for the treatment of RA patients that did not show adequate response to TNF- inhibitors .
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-6
Synonyms: IL-6; IFNB2; BSF2; HGF; HSF; BSF-2; CDF
Target Description: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable).
Ensembl: ENSG00000136244
Uniprot: P05231