【产品概况】
产品名称:Human Integrin aV / ITGAV / CD51 Antibody (Abituzumab, Research Use)
产品编号:NBR-0782
针对靶点:Integrin aV / ITGAV / CD51
抗体药商品名:Abituzumab
抗体药描述:Abituzumab(EMD-525797,DI17E6)is a new, humanized lgG (2)monoclonal antibody specificallydirected against the alpha (nu)subunit of human integrin receptorswhich is currently in phase Il clinicaltrials for the treatment of metastaticcolorectal and metastatic castration-resistant prostate cancers.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ITGAV
Synonyms: CD51; MSK8; VNRA; VTNR
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF.
Ensembl: ENSG00000138448
Uniprot: P06756