【产品概况】
产品名称:Human Integrin aV / ITGAV / CD51 Antibody (Intetumumab, Research Use)
产品编号:NBR-0783
针对靶点:Integrin aV / ITGAV / CD51
抗体药商品名:Intetumumab
抗体药描述:Intetumumab is a fully human IgG1 monclonal antibody that targets to integrin alpha-V (ITGAV), which is encoded by the ITGAV gene. This drug was developed by Centocor Inc with the expectation for the treatment of solid tumors and has been investigated in trials studying the treatment of malignant melanoma and prostate cancer recently.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ITGAV
Synonyms: CD51; MSK8; VNRA; VTNR
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF.
Ensembl: ENSG00000138448
Uniprot: P06756