【产品概况】
产品名称:Human Integrin aVb3 (ITGAV & ITGB3) Antibody (Etaracizumab, Research Use)
产品编号:NBR-0784
针对靶点:Integrin aVb3 (ITGAV & ITGB3)
抗体药商品名:Etaracizumab
抗体药描述:Etaracizumab (LM 609) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab inhibits angiogenesis and melanoma tumor growth. Etaracizumab can be used to research anticancer.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ITGAV & ITGB3
Synonyms: CD51; MSK8; VNRA; VTNR; CD61; GP3A; GPIIIa
Target Description: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF.
Integrin alpha-V/beta-3 (ITGAV:ITGB3) is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 (ITGA2B:ITGB3) is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin.
Ensembl: ENSG00000138448; ENSG00000259207
Uniprot: P06756; P05106