【产品概况】
产品名称:Human LIV-1 / SLC39A6 Antibody (LadiratuzumAb, Research Use)
产品编号:NBR-0793
针对靶点:LIV-1 / SLC39A6
抗体药商品名:LadiratuzumAb
抗体药描述:Ladiratuzumab vedotin (LV) is an investigational anti-LIV-1 antibody-drug conjugate with a protease-cleavable linker conjugated to monomethyl auristatin E (MMAE). LV 2.5 mg/kg given every 3 weeks (q3w) was generally well tolerated and has demonstrated encouraging efficacy in patients with pre-treated metastatic triple-negative breast cancer (mTNBC).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: SLC39A6
Synonyms: LIV-1
Target Description: May act as a zinc-influx transporter.
Ensembl: ENSG00000141424
Uniprot: Q13433