【产品概况】
产品名称:Human NGF / bNGF Antibody (Fasinumab, Research Use)
产品编号:NBR-0808
针对靶点:NGF / bNGF
抗体药商品名:Fasinumab
抗体药描述:Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). It is currently under investigation for the treatment osteoarthritic pain 1 and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: NGF
Synonyms: NGFB
Target Description: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems 1, 2. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival 3 (Probable).
Ensembl: ENSG00000134259
Uniprot: P01138