【产品概况】
产品名称:Human OSMR Antibody (Vixarelimab, Research Use)
产品编号:NBR-0813
针对靶点:OSMR
抗体药商品名:Vixarelimab
抗体药描述:Vixarelimab is an investigational fully-human monoclonal antibody that targets OSMRβ, which mediates signaling of interleukin-31 (IL-31) and oncostatin M (OSM), two key cytokines implicated in pruritus, inflammation and fibrosis.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: OSMR
Synonyms: N/A
Target Description: Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
Ensembl: ENSG00000145623
Uniprot: Q99650