【产品概况】
产品名称:Human Amyloid Beta Antibody (Ponezumab, Research Use)
产品编号:NBR-0816
针对靶点:Amyloid Beta
抗体药商品名:Ponezumab
抗体药描述:Ponezumab (PF-04360365) is a humanized anti–amyloid beta (Aβ) monoclonal antibody designed for treatment of Alzheimer disease (AD). It is an immunoglobulin G2 (IgG2) antibody targeted against an epitope encompassing the C‐terminal amino acids of the Aβ1-40 peptide derived from the human amyloid precursor protein (APP).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: APP
Synonyms: AD1
Target Description: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis 1.
Ensembl: ENSG00000142192
Uniprot: P05067