【产品概况】
产品名称:Human Complement C5 Antibody (Pozelimab, Research Use)
产品编号:NBR-0820
针对靶点:Complement C5
抗体药商品名:Pozelimab
抗体药描述:Pozelimab is an investigational, fully human, monoclonal antibody designed to block the activity of complement factor C5 and prevent diseases mediated by the complement pathway. It is an IgG4 antibody that binds with high affinity to wild-type and variant human C5.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: C5
Synonyms: C5a; C5b; CPAMD4
Target Description: Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Ensembl: ENSG00000106804
Uniprot: P01031