【产品概况】
产品名称:Human CTLA-4 / CD152 Antibody (Quavonlimab, Research Use)
产品编号:NBR-0824
针对靶点:CTLA-4 / CD152
抗体药商品名:Quavonlimab
抗体药描述:Quavonlimab (MK-1308) is a novel humanized immunoglobulin G1 monoclonal antibody that binds to CTLA-4 and blocks interaction with its ligands, CD80 and CD86.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CTLA4
Synonyms: CD; CD152; CELIAC3; CTLA-4; GSE; IDDM12
Target Description: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
Ensembl: ENSG00000163599
Uniprot: P16410