【产品概况】
产品名称:Human PDCD1 / PD-1 / CD279 Antibody (Balstilimab, Research Use)
产品编号:NBR-0832
针对靶点:PDCD1 / PD-1 / CD279
抗体药商品名:Balstilimab
抗体药描述:Balstilimab is an immune checkpoint inhibitor. It binds to PD-1 on T-cells, preventing ligands from interacting with the receptor. This prevents a tumor from sending signals that try to trick T-cells from attacking it. Instead, the T-cells recognize the tumor and try to kill it.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PDCD1
Synonyms: CD279; hSLE1; PD-1; PD1; SLEB2
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116