【产品概况】
产品名称:Human PDCD1 / PD-1 / CD279 Antibody (Retifanlimab, Research Use)
产品编号:NBR-0842
针对靶点:PDCD1 / PD-1 / CD279
抗体药商品名:Retifanlimab
抗体药描述:Retifanlimab (previously known as MGA012) is an investigational, humanized, proprietary anti-PD-1 monoclonal antibody being developed for use as monotherapy as well as in combination with other potential cancer therapeutics. Retifanlimab was licensed to Incyte Corporation in 2017 under a global collaboration and license agreement.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: PDCD1
Synonyms: CD279; hSLE1; PD-1; PD1; SLEB2
Target Description: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self. Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2.
Ensembl: ENSG00000188389
Uniprot: Q15116