【产品概况】
产品名称:Human TNFSF12 / TWEAK Antibody (RO5458640, Research Use)
产品编号:NBR-0850
针对靶点:TNFSF12 / TWEAK
抗体药商品名:RO5458640
抗体药描述:RO5458640 is a humanized monoclonal antibody against the TNF-like weak inducer of apoptosis (TWEAK) ligand, in Patients With Advanced Solid Tumors.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TNFSF12
Synonyms: APO3L; DR3LG; TWEAK
Target Description: Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion.
Ensembl: ENSG00000239697
Uniprot: O43508