【产品概况】
产品名称:Human TBFbR2 Antibody (LY3022859, Research Use)
产品编号:NBR-0882
针对靶点:TBFbR2
抗体药商品名:LY3022859
抗体药描述:LY3022859 is an anti-TGFβRII IgG1 monoclonal antibody that inhibits receptor-mediated signaling activation. The primary objective of this phase I study was to determine a phase II dose in patients with advanced solid tumors. Secondary objectives were to assess safety and pharmacokinetics (PK).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TGFBR2
Synonyms: MFS2; TBR-ii; TBRII
Target Description: Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3.
Ensembl: ENSG00000163513
Uniprot: P37173