【产品概况】
产品名称:Human TNFRSF10B / TRAILR2 / CD262 Antibody (Benufutamab, Research Use)
产品编号:NBR-0896
针对靶点:TNFRSF10B / TRAILR2 / CD262
抗体药商品名:Benufutamab
抗体药描述:Benufutamab (GEN1029) is a death receptor 5 (DR5) -specific agonistic antibody. Benufutamab is a mixture of 2 noncompeting DR5-specific IgG1 antibodies, each with an E430G mutation in the Fc domain. Benufutamab has antitumor effects.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TNFRSF10B
Synonyms: CD262; DR5; KILLER; TRAIL-R2; TRAILR2; TRICK2A; TRICKB
Target Description: Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
Ensembl: ENSG00000120889
Uniprot: O14763