【产品概况】
产品名称:Human ERBB1 / EGFR / HER1 Antibody (Tomuzotuximab, Research Use)
产品编号:NBR-0899
针对靶点:ERBB1 / EGFR / HER1
抗体药商品名:Tomuzotuximab
抗体药描述:Tomuzotuximab (or CetuGEX ®; Cetuximab biobetter - Glycotope; GT-MAB 5.2-GEX) is a novel monoclonal antibody (mAb) directed against the epidermal growth factor receptor (EGFR) with optimized and fully human glycosylation. Tomuzotuximab is optimized for glycosylation in its Fc domain to promote antibody-dependent cell-mediated cytotoxicity (ADCC).
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: ERBB1
Synonyms: ERRP; HER1
Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation.
Ensembl: ENSG00000146648
Uniprot: P00533