【产品概况】
产品名称:Human IL-33 Antibody (Torudokimab, Research Use)
产品编号:NBR-0903
针对靶点:IL-33
抗体药商品名:Torudokimab
抗体药描述:Torudokimab is a fully-human, clinical stage antibody that binds to the IL-33 ligand, thereby inhibiting its ability to drive Th2 response cytokines and the activation of associated cell types, including mast cells and eosinophils.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: IL-33
Synonyms: C9orf26; DKFZp586H0523; DVS27; IL1F11; NF-HEV
Target Description: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines.
Ensembl: ENSG00000137033
Uniprot: O95760