【产品概况】
产品名称:Human TNFSF5 / CD40L / CD154 Antibody (Ruplizumab, Research Use)
产品编号:NBR-0923
针对靶点:TNFSF5 / CD40L / CD154
抗体药商品名:Ruplizumab
抗体药描述:Ruplizumab (trade name Antova) is ahumanized monoclonal antibody.ltwas intended for the treatment ofrheumatic diseases like systemiclupus erythematosus and lupusnephritis, as well as the primary skinallograft rejection.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CD40L
Synonyms: GCD154; CD40L; gp39; hCD40L; HIGM1; IMD3; TNFSF5; TRAP
Target Description: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation.
Ensembl: ENSG00000102245
Uniprot: P29965