【产品概况】
产品名称:Human TGFB1 Antibody (Metelimumab, Research Use)
产品编号:NBR-0963
针对靶点:TGFB1
抗体药商品名:Metelimumab
抗体药描述:Metelimumab (CAT-192) is a human IgG4 monoclonal antibody (mAb) that neutralizes transforming growth factor beta 1 (TGF-β1) which had been chosen for further development for the treatment of diffuse cutaneous systemic sclerosis, also known as scleroderma.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: TGFB1
Synonyms: CED; DPD1; TGFB; TGFbeta
Target Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.
Ensembl: ENSG00000105329
Uniprot: TGFB1