【产品概况】
产品名称:Human IL17A, IL-17F, IL17AF Antibody (Bimekizumab, Research Use)
产品编号:NBR-0964
针对靶点:IL17A, IL-17F, IL17AF
抗体药商品名:Bimekizumab
抗体药描述:Bimekizumab is the first-in-class monoclonal antibody designed to simultaneously target IL-17A and IL-17F. Bimekizumab is currently in clinical development for psoriasis, psoriatic arthritis, and ankylosing spondylitis, with promising results.
【产品参数】
产品外观:Transparent Liquid
分子量:~150kDa
CAS:N/A
溶解度:Water; PBS, TBS Buffer等
表达系统:CHO Expressed
抗体亚型:Ab. Isotype - IgG
【基因信息】
Gene Name: CTLA-8
Synonyms: IL-17A; IL-17; CTLA8
Target Description: IL17A (Interleukin 17A) is a Protein Coding gene. Diseases associated with IL17A include Allergic Contact Dermatitis and Bronchiolitis Obliterans. Among its related pathways are MIF Mediated Glucocorticoid Regulation and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is IL17F.
Ensembl: ENSG00000112115
Uniprot: Q16552