Ubiqbio | UbiQ-057 | Ub-PA

品名：Ub-PA

货号：UbiQ-057

规格：50 µg

品牌：Ubiqbio

产品描述

a potent and specific inhibitor of deubiquitylating enzymes (DUBs)

Ubiquitin-propargylamide is a potent and specific inhibitor of deubiquitylating enzymes (DUBs). This activity probe can be used for activity profiling experiments and determining DUB inhibitor specificity. It has two unique capabilities: It forms a covalent linkage with (the active site Cys residue of) a DUB that can be cleaved by acid treatment (5% aq. TFA), allowing for proteomic analyses. It targets all three major DUB families: UCH, USP and OTU.

Applications: Crystallization, Pull down, Purification, Western Blot, MS, NMR, Phenotypic protein profiling

Category: activity-based probes