| 产品名称 | Ubiqbio | UbiQ-117 | SUMO2-Dha |
|---|---|
| 目录号 | UbiQ-117 |
| 别名 | SUMO2-Dha |
| 外观 | 见COA |
| 分子量 | N/A |
| CAS | N/A |
| 溶解度 | |
| 存储条件 | 见COA |
| 保存时间 | 见COA |
| 备注1 | |
| 备注2 |
| 目录号 | 规格 | 价格 | 库存状态 | |
| UbiQ-117 | 50 µg | 咨询 | 咨询 |
Ubiqbio | UbiQ-117 | SUMO2-Dha
品名:SUMO2-Dha
货号:UbiQ-117
规格:50 µg
品牌:Ubiqbio
产品描述
an activity-based probe for the SUMO ligation pathway
SUMO2-Dha (UbiQ-117) is an activity-based probe for the SUMO ligation pathway. It is based on the SUMO2 sequence in which the C-terminal Gly has been replaced by a dehydroalanine (Dha) residue. The native Cys48 has been mutated to a Ser residue. UbiQ-117 is processed in a native manner by SUMO E1, E2 and E3 ligases and during this process, it forms an electrophilic intermediate that can react with the active site Cys residue of the E1, E2 and E3 enzymes, thereby creating a covalent bond.
Applications: Crystallization, Western Blot
Category: activity-based probes