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产品名称 Ubiqbio | UbiQ-117 | SUMO2-Dha
目录号 UbiQ-117
别名 SUMO2-Dha
外观 见COA
分子量 N/A
CAS N/A
溶解度
存储条件 见COA
保存时间 见COA
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目录号 规格 价格 库存状态  
UbiQ-117 50 µg 咨询 咨询


Ubiqbio | UbiQ-117 | SUMO2-Dha


品名:SUMO2-Dha

货号:UbiQ-117

规格:50 µg

品牌:Ubiqbio


产品描述

an activity-based probe for the SUMO ligation pathway

SUMO2-Dha (UbiQ-117) is an activity-based probe for the SUMO ligation pathway. It is based on the SUMO2 sequence in which the C-terminal Gly has been replaced by a dehydroalanine (Dha) residue. The native Cys48 has been mutated to a Ser residue. UbiQ-117 is processed in a native manner by SUMO E1, E2 and E3 ligases and during this process, it forms an electrophilic intermediate that can react with the active site Cys residue of the E1, E2 and E3 enzymes, thereby creating a covalent bond.

Applications: Crystallization, Western Blot

Category: activity-based probes

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