Ubiqbio | UbiQ-156 | Biotin-Ahx-SUMO2-VME

品名：Biotin-Ahx-SUMO2-VME

货号：UbiQ-156

规格：50 µg

品牌：Ubiqbio

产品描述

a potent, irreversible and specific activity-based probe for SUMO proteases, labeled with biotin on the N-terminus

UbiQ-156 is an activity-based probe for SUMO proteases. It is based on the human SUMO2 sequence (C48S) in which the C-terminal is equipped with the electrophilic vinyl methyl ester (VME) group. The N-terminus is labeled with biotin and an aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and SUMO2 protein for efficient access of biotin binding entities. It has been prepared by total chemical synthesis and is therefore well-defined in terms of biotinylation site.

Applications: Crystallization, Pull down, Purification, Western Blot, Phenotypic protein profiling, DUB activity profiling, Target inhibitor profiling

Category: activity-based probes