Ubiqbio | UbiQ-168 | Biotin-Ahx-SUMO2-PA

品名：Biotin-Ahx-SUMO2-PA

货号：UbiQ-168

规格：50 µg

品牌：Ubiqbio

产品描述

an activity-based probe for SUMO proteases, tagged with biotin on the N-terminus

UbiQ-168 is a mechanism activity-based probe for SUMO proteases. It is based on the human SUMO2 sequence (C48S) in which the C-terminal Gly has been replaced by the propargylamide (PA) electrophile. The N-terminus is labeled with biotin and an aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and Ub protein for efficient access of biotin binding entities. It has been prepared by total chemical synthesis and is therefore well-defined in terms of biotinylation site.

Applications: Crystallization, Pull down, Purification, Western Blot, Phenotypic protein profiling, DUB activity profiling, Target inhibitor profiling

Category: activity-based probes