Ubiqbio | UbiQ-L05 | DUB activity-based probe mix – Biotin tagged

品名：DUB activity-based probe mix – Biotin tagged

货号：UbiQ-L05

规格：panel

品牌：Ubiqbio

产品描述

UbiQ-L05 is a panel of three activity-based probes for deubiquitinating enzymes (DUBs) (50 μg each).

UbiQ-L05 is a panel of three activity-based probes for deubiquitinating enzymes (DUBs) (50 μg each). The probes are based on ubiquitin and labeled on the N-terminus with a biotin tag. A 6-aminohexanoic acid (Ahx) linker is used to create extra space between the biotin and Ub N-terminus for efficient access of biotin binding entities. By mixing the three probes, a highly DUB-reactive probe mix is obtained that contains the combined reactivity of the PA (propargyl amide), VME (vinyl methyl ester), and VS (vinyl sulfone) electrophiles. As a result the labelling efficiency of the mix is higher than using each probe separately.

Applications: Crystallization, Pull down, Purification, Western Blot, MS, NMR, Phenotypic protein profiling

Category: activity-based probes, explorer panels