品名: 15N, Alpha-Synuclein, Uniform Label

货号: S-1004-1

规格: 0.5 mg

品牌：rPeptide

储存温度：-20℃

序列：MDVFMKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH GVATVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFVKKDQL GKNEEGAPQE GILEDMPVDP DNEAYEMPSE EGYQDYEPEA

来源：Recombinant. A DNA sequence encoding the human alpha-synuclein sequence was expressed in E. coli, with N15 as the nitrogen source.

描述：15N Uniform labeled Alpha-Synuclein (α-Synuclein) has all nitrogen’s N15 labeled. α-Synuclein is a 14 kD (140 amino acids) acidic presynaptic protein. It is a major component of Parkinson’s disease aggregates and is implicated in the pathogenesis of Parkinson’s Disease and related neurodegenerative disorders. α-Synuclein accumulates in the brains of sporadic Parkinson’s disease patients as a major component of Lewy bodies, which are intraneuronal cytoplasmic inclusions characteristic of Parkinson’s disease. α-Synuclein appears to associate with other proteins that aggregate and is found in β-amyloid plaques and neuritic tangles in Alzheimer’s disease 3 .

分子量：14,624 Da

纯度：>95% by SDS-PAGE and Mass Spec.