品名: P7C3

货号: N-3004-2

规格: 25 mg

品牌：rPeptide

储存温度：-20℃

序列：N/A

来源：N/A

描述：P7C3 exerts proneurogenic activity by protecting newborn neurons from apoptosis. Prolonged administration to aged rats impedes neuronal death and preserves cognitive capacity[1]. Delays disease progression in G93A-SOD2 mutant mouse model of amyotrophic lateral sclerosis[2]. Blocks MPTP-mediated cell death of dopaminergic neurons in the substantia nigra of adult mice, a model of Parkinson disease[3]. Restores hippocampal neurogenesis in a mouse model of Down Syndrome[4]. The mechanism of action involves activation of nicotinamide phosphoribosyltransferase (NAMPT) with concomitant increase of intracellular levels of NAD[5]. Active in vivo.

分子量：474.2

纯度：>98%